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Makan Bibi. Khusnu Ali. Japia Kamrup. 30-11-08/. 5721. GMCH. Pratilata Saikia.
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KT 5720 is a hexylester derivative of K-252a that is a potent and selective inhibitor of PKA.2 KT 5720 has been used in many studies to characterize the role of PKA in various cellular and physiological events. For example, PKA activators suppress lectin-induced apoptosis of human leukemia HL-60 cells. The subsequent addition of KT 5720 KT 5720 is an inhibitor of PKA. KT5720 attenuates hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents, decreasing amplitude and increasing action potential threshold. This inhibition results in decreases in intracellular Ca2+ levels and suppression of dorsal root ganglion (DRG) neuron excitability. KT5720 is a kinase inhibitor with specificity towards protein kinase A. It is a semi-synthetic derivative of K252a and analog of staurosporine. Scientific background KT5720 is a semi-synthetic derivative of K525a.
sammanställning A B C D E 1 kaprogr F 2 3 Summa av itid
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Khusnu Ali. Japia Kamrup. 30-11-08/. 5721. GMCH.
Stockholm stadsbibliotek
, 4 k a p . 7 §.
Sida 928; Original. 256. Kungl.
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73 5720, ansvarig. 5721, ##ums.